PubMed publicaties

Sinds begin jaren 60 zijn er veel wetenschappelijke artikelen gepubliceerd over de schadelijke effecten van Softenon op de ongeboren vrucht en op de ouder wordende Softenon slachtoffers. Een verzameling van de meest recent gepubliceerde artikelen vindt u hieronder. De volledige lijst met titels en abstracts kunt u vinden, door hier te klikken.

2017 Impact Thalidomide use Brazil. Er wordt met een kritische blik gekeken naar de geschiedenis van Thalidomide in Brazilie en naar het voorkomen van Thalidomide Embryopathie in de afgelopen decennia.

2015 Blood pressure in thalidomide-impaired patient. Een publicatie van anesthesie bij een Softenon slachtoffer zonder armen en met benen waarbij ovariumcystectomie wordt uitgevoerd.

Jul 2024 Clinical efficacy of thalidomide for various genotypes of beta thalassemia.
The objective of this study was to investigate the therapeutic efficacy of thalidomide across various genotype presentations of β-thalassemia so as to facilitate the early screening of thalidomide-sensitive thalassem...

2024 Activity of apremilast in a patient with severe pemphigus vulgaris: case report.
Although the treatment for pemphigus vulgaris (PV) has been revolutionized by the use of rituximab combined with corticosteroids, new effective therapies with a better safety profile are needed.

Jul 2024 Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature.
Central nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous system involvement in chronic lymphocytic leukemia. This article aims to analyze t...

Dec 2024 Risk of neutropenia in psoriasis patients prescribed anti-IL-23 antibody in comparison with anti-IL-17 antibody or adalimumab based on real-world data from the MID-NET in Japan.
To evaluate the risk of neutropenia during treatment with anti-IL-23 antibodies in patients with psoriasis.

Dec 2024 Treatment pattern among patients with relapsed/refractory multiple myeloma (RRMM) who had received pomalidomide-based regimens in Taiwan.
The treatment landscape of relapsed/refractory multiple myeloma (RRMM) is rapidly evolving in Taiwan. The present study aimed to assess the treatment patterns among RRMM patients in Taiwan.

Dec 2024 Deucravacitinib onset of action and maintenance of response in phase 3 plaque psoriasis trials.
In the global phase 3 POETYK PSO-1 and PSO-2 trials, significantly greater proportions of deucravacitinib-treated patients met the coprimary endpoints (PASI 75, sPGA 0/1) at Week 16 versus placebo or apremilast-treate...

Jun 2024 Multiple myeloma.
Multiple myeloma (MM) is a haematological lymphoid malignancy involving tumoural plasma cells and is usually characterized by the presence of a monoclonal immunoglobulin protein. MM is the second most common haematolo...

Jun 2024 Molecular Long-Term Analysis of the GMMG-HD4 Trial in Multiple Myeloma-Patterns of Association of Chromosomal Aberrations with Response and Proliferation Determining Survival in Selecting Treatments in View of Limited Resources in Low- and Middle-Income Countries.
Based on the lack of differences in progression-free and overall survival after a median follow-up of 93 months in our HOVON-65/GMMG-HD4 trial (German part; = 395) randomizing VAD induction (vincristin/adriamycin/dex...

Jun 2024 Preclinical Evaluation of a Novel Series of Polyfluorinated Thalidomide Analogs in Drug-Resistant Multiple Myeloma.
Immunomodulatory imide drugs (IMiDs) play a crucial role in the treatment landscape across various stages of multiple myeloma. Despite their evident efficacy, some patients may exhibit primary resistance to IMiD thera...

Jul 2024 Multicolumn Nanoflow Liquid Chromatography with Accelerated Offline Gradient Generation for Robust and Sensitive Single-Cell Proteome Profiling.
Peptide separations that combine high sensitivity, robustness, peak capacity, and throughput are essential for extending bottom-up proteomics to smaller samples including single cells. To this end, we have developed a...